Can Vitamin B-Complex Aggravate the Carbamazepine Induced Toxic Epidermal Necrolysis?

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Can vitamin B-complex aggravate the carbamazepine induced toxic epidermal necrolysis?

Toxic Epidermal Necrolysis (TEN), which is also known as Lyell's syndrome, is a widespread, life-threatening, mucocutaneous disease that is particularly observed secondary to drugtaking and less commonly secondary to infections and immunization. Carbamazepine is associated with benign pruritic rash in 10-15% of the patients, but the life threatening dermatological syndromes like exfoliative der...

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Toxic Epidermal Necrolysis (TEN) which is characterized by the detachment of the epidermis from the dermis is a rare (1.89/1.000.000 annually) and potentially life-threatening condition. The overall mortality is 20 - 30%. TEN is characterized by sudden apoptosis of keratinocytes leading to mucous membrane erosions and epidermal detachment; detachment of less than 10% of the total body surface a...

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ژورنال

عنوان ژورنال: JOURNAL of CLINICAL AND DIAGNOSTIC RESEARCH

سال: 2012

ISSN: 2249-782X

DOI: 10.7860/jcdr/2012/4744.2566